Primary aldosteronism, also known as number one hyperaldosteronism or Conn's syndrome, refers to the excess production of the hormone aldosterone from the adrenal glands, ensuing in low renin levels. This abnormality is caused by hyperplasia or tumors. Many be afflicted by fatigue, potassium deficiency and excessive blood stress which may purpose negative vision, confusion or headaches. Symptoms might also consist of: muscular aches and weakness, muscle spasms, low back and flank pain from the kidneys, trembling, tingling sensations, numbness and immoderate urination. Complications include cardiovascular disease which includes stroke, myocardial infarction, kidney failure and atypical heart rhythms.
Primary hyperaldosteronism has some of causes. About 33% of cases are due to an adrenal adenoma that produces aldosterone, and 66% of instances are due to an enlargement of both adrenal glands. Other unusual causes include adrenal cancers and an inherited disorder called familial hyperaldosteronism. Some advocate screening people with high blood strain who are at improved risk, even as others recommend screening each person with high blood strain for the disease. Screening is generally carried out by means of measuring the aldosterone-to-renin ratio within the blood, with similarly trying out used to verify positive results. While low blood potassium is classically defined in number one hyperaldosteronism, this is only found in about a quarter of human beings. To decide the underlying purpose, clinical imaging is carried out.