Insulin Analogues and Glucose Sensors

An analogue refers to something that is similar or “analogous” to something else. Therefore, “insulin” analogue are analogue that have been designed to mimic the body’s natural sample of insulin release. These synthetic-made insulins are the analogue of human insulin. However, they have minor structural or amino acid modifications that supply them special applicable characteristics when injected beneath the skin. Once absorbed, they act on cells like human insulin, however, are absorbed from fat tissue more predictably. They are of two types namely:

  • Rapid-acting injected insulin analogue
  • Long-acting injected insulin analogue

A tiny glucose-sensing device known as a "sensor" is inserted just underneath the skin (subcutaneous tissue). It's very much like the insertion of an insulin pump catheter. Sensors are typically inserted inside the stomach or higher buttock area, and tape is used to maintain them in place. The sensor measures the extent of glucose in the interstitial fluid (fluid surrounding the cell) every 10 seconds and changes it into an electrical signal. The signal represents the quantity of sugar inside the blood.